Symptoms of High Acetylcholine Levels (Symptoms/Signs of Excess Acetylcholine)

Before I get into the grain of this article, I'd just like to point out that the only formal, similar article, over there on MindRenewal.US' , has been on there, on top-ranking results of Google, for over 20+years with no contestment. The issue with it, and though I appreciate the effort, is that the basis of the article is two specific sources that all relate back to Depressive disorders, and some of the symptoms listed are either garbled in their ''sources'' , where they are unlikely to be found, or clearly not even within those sources nor an extension of them. Instead, some of the 'symptoms' they list seem to be a result of internal bias, and jumpy conclusions which may be abrogated if countersourced. 

Let me also say that what is ''high'' acetylcholine, may not be sufficient for another individual, due to genetic and receptor-concentration related differences. Some may have no side-effects or symptoms from raising acetylcholine x10 (!)... 

In fact, elevated acetylcholine levels may produce no symptoms in a vast majority of individuals. Elevated acetylcholine is not guaranteed by any means to produce negative effects, and acetycholine produces different effects depending on the circumstance, and even the environment (!!)...

With that being said, let's get this show (or rather, lesson) started.

~Physical Symptoms of Excessive Acetylcholine~

• Bradycardia (Low Heart Rate) (1) (2) (3)
• Hypotension (Low Blood Pressure) (4) (5)
• Hypersalivation (abnormal abundancy of saliva) (6) (7)
• Excess Sweating (8) (9)
• Tearing: Frequent, Spontaneous, Unusual Tearing (also known as lacrimation..) (10) (11) (12)
• Hypo or Hyperthermia (low or high body temperature, feeling cold or feeling Hot) (13) (14)
• Weak Muscles (15) (16)
• Muscle Spasms, or little twitchy sensations underneath the skin that resemble bugs being underneath (!See Here!) (18) (7)
• Itching, especially contact itching, such after exposure to external influences of hot or cold water, mold, grass, dust, ticks, and other outside/wilderness influences (19) (20) (21)
• Frequent Nausea, or Incredible (Remarkable) Susceptibility to Motion & Sea Sickness [!] [!-!]

Mental Health Effects of High Acetylcholine

• ..Depressive Like Behavior (22) (23) 
• Anhedonia (24) (25)
• Spaciness & Passivity (Blank-Mind, no particular thoughts in Mind, lack of Zest for Life) (26) (27) (28)
• Increased Display of Distaste / Voicing of Distaste (increased blunt behavior, objective aversion and in some ways, animated behavior) (29) (30)
• Impulsivity (31) (32)
• Over-thinkin' it (Overthinking a simple situation, or analyzing past what is necessary, even for an ordinary task) (33) (34) (35)
• An Occasional or Frequent Master of Redirection (Good at redirecting conversations, or diverting the current topic, or simply distraction) (36) (37)
• Intellectually Dominant, but Poor Common Sense (similar to the low norepinephrine Profile) (38) (39) (40) (41) (42) (43)..
• Agitation associated with Dysphoria (more prone to Agitation due to Dysphoria) (44) (45) (46)

││FOUNDATION SOURCES││

(!) University of Washington - School of Medicine - Acetylcholine as a Neurotransmitter (!)

(!) Yale Scientific - Uncovering the Biochemical Basis of Depression (!)

 (!) Neuropsychopharmacology: The Fifth Generation of Progress (!)
(!) The Role of Acetylcholine Mechanisms in Affective Disorders (!)

KIN450-Neurophysiology

Clin Dermatol. Author manuscript; available in PMC 2013 Jun 24.

Published in final edited form as:

Clin Dermatol. 2013 Jan-Feb; 31(1): 31–40.

doi:  10.1016/j.clindermatol.2011.11.004

PMCID: PMC3690364

NIHMSID: NIHMS468460

Psychosomatic factors in pruritus

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151339/

WHICH PESTICIDES CAN INHIBIT CHOLINESTERASE?

~ AUTONOMIC NERVOUS SYSTEM Explanation ~