Herbs/Supplements to Increase 5-HT2A Receptors (How to Increase 5-HT2A Receptors Naturally)

Now, I may not agree with every separate reasoning why one would want to 'increase 5-HT2A receptors' nor am I a pro-serotonin guy, but there is that undeniable fact that increasing 5-HT(2)A receptors (AKA Serotonin S2 Receptors) will render one more sensitive to the dissociative and psychedelic-effects of various psychoactive drugs [1] [2] [3]. Let's be more clear though, increasing serotonin type 2A receptors is able to confer the following benefits.

• Rendering one sensitive to mushrooms, salvia, molly and what have you, the effects of all hallucinogenic drugs become more apparent, and one loses their tolerance to them [4] [5].
• It's possible that increasing this receptor subtype may stimulate the mesolimbic system in the brain and thus increase creativity and maybe even 'magical thinking' [6] [7].
• Increasing this receptor would increase cortisol secretion [8] [9], so it's possible that some would find benefit from doing so if you they suffer from hypoadrenalism or Addison's disease.

As far as other reasoning, some may increase the receptor just merely to experience the effects, or increasing it may cause behavioral changes which may mimic, or reproduce a long-lost mania. 

Therefore there are some *benefits* if you will, but that doesn't mean this strategy is for everyone. I would not recommend utilizing the practices in this guide if you suffer from any of the following.

1. Obsessive-Compulsive Disorder.
2. Schizophrenia.
3. Mania.
4. Stress-Issues.
5. Borderline Personality Disorder.

All of those above issues are outlined by too much serotonin 5-HT2A activity so increasing it further would be foolish if one has those disorders or a predisposition to such.

Now onto the supplements.

(Increasing 5-HT2A/S2 Receptors Naturally with Supplements)

View the exclamation marked box to go to the source or citation in question.

1.) Inositol [!]. Inositol is probably the cheapest way to increase serotonin 2A receptors though it depends on what form you buy. I recommend this one.

2.) St.John's Wort Extract [!]. A powerful herb and anti-depressant which is well-known for sensitizing oneself for the experiences of the mystical and psychedelic chemicals. <Buy it Here>

3.) Ashwagandha [!]. Another anti-depressant and anti-anxiety herb that increases serotonin 2A receptors. It is one of the most notorious anti-anxiety herbs on the planet and almost everyone has success with it. {I recommend Barlowe's brand.}

NOTE: Using all of these at once, each daily, may increase the effects of each other and increase receptors that many times as much as one alone, but may also produce side-effects and interact too much with your other regimen.

St.John's Wort can not be take with psychedelic drugs, it must be taken for at least 3 weeks BEFORE ingesting or smoking any psychedelics.

**OTHER SOURCES / CITATIONS**

• A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults
• Inositol For Anxiety Disorders: An Effective Treatment?
• 5HT2A Receptors: A Root Cause of Anxiety, Fatigue, Sleep Problems and CIRS