Area-1255 : is here again with another 'outside the box' article. This time we will be exploring the differences between high and low endorphin symptomology ; this will give us a sort of 'routine' to deliberate on before making any particular medical decisions and / or consultations.
*MANY* (but not all) endocrine disorders (hormone disorders) stem from dysfunctional opioid systems (1) in the Brain, Spinal Cord and Peripheral Nervous System (2). This includes receptor downregulation and / or supersensitivity (3).
This is demonstrated, not just in opioid dependent individuals but Also those with congenital (from birth) opioid-receptor mutations/polymorphisms (4) (5) (6) (7).
Here we will go over the acute and long-term effects of physiological opioid-function abnormalties and endorphin imbalance/s.
The SYMPTOMS of Very HIGH β-Endorphin and / or DYNORPHIN levels (includes naturally or genetically) are...
- Social Isolation, and low social motivation (8) (9)
- Impulsivity (due to excess Kappa/k-opioid activation, dynorphin mediated) (10) (11) (12)
- Depression or Anhedonia (Emotional Numbness) (13) (14)
- Low/Absent Sex Drive (15) (16) (17) (18)
- Low Testosterone / Universal Hypogonadism in either Sex (19) (20) (21) (22) (23) (24)
- Infertility : in both Men and Women ; Low Sperm Count, Lack of ovulation (25) (26) (27) :-: (28) (29) (30)
- COGNITIVE INFLEXIBILITY (unable to switch Tasks easily and unable to understand or unwillingness to Internalize what one is not used to; unable to pick up new 'concepts' and generally resorts to what one knows) (31) (32) (33) (34) (35)
- Indifference, lack of competitive behavior, doesn't care about 'Winning' or 'Losing' (36) (37).
- EXTREME FATIGUE / LETHARGY (38) (39) (40) (41)
- Lack of the Ability to ''Cry''. (42) (43) (44)
- Constipation (45) (46)
To correct most of those issues you must.
- Resolve the underlying hormonal imbalance (too much Progesterone or Estrogen etc)
- Use Naltrexone in the short-term if no anxiety disorder is present. (25-50 mg once per day)
- Use Cialis to counter-act the sexual deficits in the short-term. (5-20 mg once per day)
TO Permanently SOLVE Opioid IMPOTENCE & Sexual Deficit as well as REVERSING/CORRECTING NATURALLY HIGH OPIOID-ENDORPHIN AXIS LEVELS, simply Click the ~Image~ below.
The SYMPTOMS of Very LOW β-Endorphin and / or DYNORPHIN levels (includes naturally or genetically) are...
- Anxiety; especially anticipatory Anxiety (47) (48)
- Residual Ruminations (feelings of excess/persistent dread or tremor after traumatic/stress event/s) (49)
- Risk-Taking Behavior (living ''on edge'') (50) (51)
- Loves working Out; sometimes to the Point of 'over-training'. (52)
- Workaholicism and Fast, Intuitive, Bright and Dedicated mind, but with underlying internal anxiety and persistent emotional fastening/Reservations. (53) (54)
- Depressive, even Suicidal tendencies in *some* individuals Affected. (depends on other factors; such as psychosocial status , income, past experiences and personality traits as well as belief system influence/s) (55)
- Rigorous 'testing' or even compulsive behavior; constant checking; O.C.D (!)
**It is important to note that both high and low beta-endorphin levels can lead to obsessive-compulsive disorder**.

