The Natural Serotonin Blockers. Now you may ask why would someone want to block or antagonize serotonin? Well...some people naturally have a little too much, to the point where it causes autonomic dysfunction.... or perhaps you are trying to augment the effects or reduce the effects of an SSRI anti-depressant? In which case the following may be helpful.
It is shown that "Panax Ginseng" is a potent serotonin antagonist. It blocks human serotonin 5-HT(3) receptors and thus stops nausea in it's tracks(1)(2)(3). It also directly decreases serotonin in the hypothalamus and inhibits exercise induced increases in serotonin(4)(5).
Ginseng also acts as a noncompetitive nicotinic receptor antagonist and also inhibits Calcium Channels and Sodium Channels(6)(7).
You can buy a super potent red panax ginseng extract below, guaranteed serotonin antagonist.
PRODUCT ONE
The next Natural serotonin antagonist is called "Shilajit".
Shilajit was found to decrease both total and neuronal serotonin levels, especially in the hypothalamus.
http://www.sabinsa.com/products/standardized-phytoextracts/shilajit/shilajit.pdf
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296184/
It also blocks the enzyme "AcHe" which helps sustain elevated Acetylcholine levels; which in turn lowers serotonin production!
Shilajit is thus a very potent Pro-Cognitive supplement that also lowers serotonin.
Recommended Shilajit Product is below!
The THIRD Natural OTC Serotonin Antagonist would be something called "Vitex Agnus Castus" extract, and this mechanism probably accounts for a great deal of why it also strongly inhibits prolactin levels in both men and women(8)(9)(10)
However, Vitex also exerts significant progestogenic activity, and I don't recommend this product for men necessarily.
And the FOURTH natty serotonin antagonist is one that is often heard about.
Yohimbe Bark Extract
Be careful as the product can be VERY stimulating.
Thanks so much for this Jason! A few months back my boyfriend lost his libido and had chronic diarrhea from taking SSRI pills and antidepressants, we examined and used different stuff, including viagra, cialis and some natural hormone boosters (testosterone boosters)...but none availed. finally we tried the suggestions in your article for blocking serotonin. and omg! it came back and he's feeling more better n less depressed n has his libido back! specifically we are using the products mentioned in this article the shilajit and ginseng. he also had his testosterone levels go way up in blood work. he said he will post here when he has it all together !
ReplyDeletethanks again jason!
What brand of Ginseng are you using?
ReplyDeleteCurrently I am using Barlowe's : http://ow.ly/uU403070wRK
DeleteWhat I'm finding in my search for OTC serotonin blockers is that people take the exact products above in order to INCREASE their serotonin levels. I am really confused.
ReplyDeleteIs that so? Nobody uses Shilajit, Vitex or Yohimbe to raise serotonin, they are all well-established ``blockers``, so wherever you are getting your information from is wrong - or you are simply a troll post.
Deletehey I have a question .. is this Shilajit High Mountain Dragon Herbs the best shilajit? how are you sure it is ? also I read a comment that said if Shilajit has not 50% fulvic acid its waste of time this one says it has 40%. whats up with that? Anyway I ordered the one you suggested I really hope it can fix my exess amount of serotonin I have.... Gonna start with 4 pills and see how I feel. I really appericate your help also, If it wasnt for you I would have nowhere else to look for ways to reduce serotonin , not many places teach you how to do that.. thanks
ReplyDeleteIts the best capsule form, but the Tibetan Shilajit Paste offered by Barlowes.com is super good too! Look at our recent posts for June 2017.
DeleteIts the best capsule form, but the Tibetan Shilajit Paste offered by Barlowes.com is super good too! Look at our recent posts for June 2017.
Deletehi im trying white willow bark right now i took 1800mg. how long does it to see a decrease in serotonin?? do i need higher dose
ReplyDeleteI wouldn't take more than 1800mg to avoid stomach irritation or something. For me it works right away, but I don't have excess serotonin. When I take 4 capsules 1600mg I feel very depressed, I rarely use white willow bark.
ReplyDeletesorry i miscalculaced it was 5 pills = 2000mg but yeah I felt effect right away too man. does it just get better (as in keep reducing serotonin ) or is this it? im happy just with this to be honest .
ReplyDeleteWhat is the one that you're taking? I'm taking Natures Way. What do you feel, better or worst? I take more often Corydalis a dopamine antagonist, and that one makes me feel better.
ReplyDeletethis 1 http://www.ebay.co.uk/itm/291599702810?_trksid=p2060353.m2749.l2649&ssPageName=STRK%3AMEBIDX%3AIT
ReplyDeletei do feel a little more sad so i guess its working. I just have to get used to this serotonin decrease .
But why do you want to decrease serotonin?
ReplyDeletebecause I produce way more than the normal person would its genetics for me not sure what its causing it.
ReplyDeletea theory is I have low-functioning MAO-A, which means my serotonin doesn't get broken down as quickly.
The study mentioned doesn't justify Willow Bark as an antagonist, I've seen it mentioned on Ray Peat but I think for the most part; Shilajit, Yohimbine & BCAA are more effective.
ReplyDeleteThe study mentioned doesn't justify Willow Bark as an antagonist, I've seen it mentioned on Ray Peat but I think for the most part; Shilajit, Yohimbine & BCAA are more effective.
ReplyDeletei do feel more sad so it but be decreasing my levels .. but yeah im waiting for all the 4 you mentioned in this article I ordered them to arrive.. cant wait.... which one should I try first? should I combine them so it decrease my serotonin even more? also you say bcaa can decrease serotonin? how much would I need to take of bcaa? I remembered I tested this once but maybe my dose wasnt enough? I read someone took like 20g to keep his serotonin lvls down..
ReplyDeleteupdate been like 2 days.. I do feel different but its not doing it for me i still have severe social anxiety.. does it have to build up in ur system?
ReplyDeletethis was from the source you linked´´In the open field behavior test, processed Shilajit and the isolated active constituents showed
ReplyDeletesignificant efficacy in diminishing anxiety symptoms. However, native Shilajit was not very
effective, probably on account of the free radical contamination in such material, further
validating the need for purification´´
is the dragon shiljait processed or native?? I dont quite understand that sentence.